Technology plays a pivotal role in modern university curriculum. Given the recent advances in machine learning, it is particularly important to leverage the tools provided by the latest advances in computing. In this paper, we investigate the effects of including Python-based computer algebra system SymPy in university calculus courses. The advantages of SymPy include open-source, introduction to programming, and simplicity. Critically, comparison of the grades pre and post adoption of SymPy in calculus courses indicates a statistically significant improvement. Although further studies - based on a larger cohort - about the effectiveness of open-access computer algebra system are desirable, the initial findings suggest that SymPy provides a viable alternative to commercially available computer algebra system.