Despite the exponential growth in STEM-related jobs, there is an acute shortage of people choosing to pursue STEM-related studies and careers. Compared with men, women are underrepresented in STEM-related courses and careers. The chapter, therefore, examined the associations of perceived usefulness of 3D printing technology, self-concept in using 3D printing technology, and interest in and enjoyment of using 3D printing technology with interest in science-, math-, and technology-related careers among 276 female elementary students enrolled in public schools in Abu Dhabi, United Arab Emirates. The results of path analyses after accounting for student demographic characteristics, revealed that perceived usefulness of 3D printing technology, self-concept in using 3D printing technology, and interest in and enjoyment of using 3D printing technology were significantly and positively related to interest in science-, math-, and technology-related careers among female elementary students. Implications of the findings for policy and practice are discussed.